Targeted core-shell nanoparticles for precise CTCF gene insert in treatment of metastatic breast cancer

Targeted core-shell nanoparticles for precise CTCF gene insert in treatment of metastatic breast cancer

Clustered regularly interspaced short palindromic repeats (CRISPR) technology emerges a remarkable potential for cure of refractory cancer like metastatic breast cancer. However, how to efficiently deliver the CRISPR system with non-viral carrier remains a major issue to be solved. Here, we report a...

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Bibliographic Details
Main Authors: Jialun Duan, Chunjie Bao, Ying Xie, Haitao Guo, Yixuan Liu, Jianwei Li, Rui Liu, Peishan Li, Jing Bai, Yan Yan, Limin Mu, Xueqi Li, Guiling Wang, Wanliang Lu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-05-01
Series:Bioactive Materials
Subjects:
Core-shell nanoparticles
Non-viral gene delivery
Precise gene editing
CTCF
Metastatic breast cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21004576

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http://www.sciencedirect.com/science/article/pii/S2452199X21004576

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