Lessons From APOL1 Animal Models

African-Americans have a three-fold higher rate of chronic kidney disease compared to European-Americans. Much of this excess risk is attributed to genetic variants in APOL1, encoding apolipoprotein L1, that are present only in individuals with sub-Saharan ancestry. Although 10 years have passed sin...

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Bibliographic Details
Main Authors: Teruhiko Yoshida, Khun Zaw Latt, Jurgen Heymann, Jeffrey B. Kopp
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.762901/full