Challenges and opportunities for T cell-mediated strategies to eliminate HIV reservoirs

HIV’s ability to establish latent reservoirs of reactivation-competent virus is the major barrier to cure. Shock and kill methods consisting of latency reversing agents (LRAs) followed by elimination of reactivating cells through cytopathic effects are under active development. However, the clinical...

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Bibliografische gegevens
Hoofdauteurs: Mark Alan Brockman, R. Brad eJones, Zabrina Lesley Brumme
Formaat: Artikel
Taal:English
Gepubliceerd in: Frontiers Media S.A. 2015-10-01
Reeks:Frontiers in Immunology
Onderwerpen:
Online toegang:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00506/full