Mouse Models of Cardiomyopathies Caused by Mutations in Troponin C

Mouse Models of Cardiomyopathies Caused by Mutations in Troponin C

Cardiac muscle contraction is regulated via Ca<sup>2+</sup> exchange with the hetero-trimeric troponin complex located on the thin filament. Binding of Ca<sup>2+</sup> to cardiac troponin C, a Ca<sup>2+</sup> sensing subunit within the troponin complex, results in...

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Bibliographic Details
Main Authors: Svetlana B. Tikunova, Jenna Thuma, Jonathan P. Davis
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
troponin
cardiomyopathy
cardiac
thin filament
contraction
relaxation
Online Access:https://www.mdpi.com/1422-0067/24/15/12349

Internet

https://www.mdpi.com/1422-0067/24/15/12349

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