Widespread dysregulation of MiRNAs by MYCN amplification and chromosomal imbalances in neuroblastoma: association of miRNA expression with survival.

Widespread dysregulation of MiRNAs by MYCN amplification and chromosomal imbalances in neuroblastoma: association of miRNA expression with survival.

MiRNAs regulate gene expression at a post-transcriptional level and their dysregulation can play major roles in the pathogenesis of many different forms of cancer, including neuroblastoma, an often fatal paediatric cancer originating from precursor cells of the sympathetic nervous system. We have an...

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Bibliographic Details
Main Authors: Isabella Bray, Kenneth Bryan, Suzanne Prenter, Patrick G Buckley, Niamh H Foley, Derek M Murphy, Leah Alcock, Pieter Mestdagh, Jo Vandesompele, Frank Speleman, Wendy B London, Patrick W McGrady, Desmond G Higgins, Anne O'Meara, Maureen O'Sullivan, Raymond L Stallings
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2773120?pdf=render

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http://europepmc.org/articles/PMC2773120?pdf=render

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