Melatonin MT1 receptors as a target for the psychopharmacology of bipolar disorder: A translational study

Melatonin MT1 receptors as a target for the psychopharmacology of bipolar disorder: A translational study

The treatment of bipolar disorder (BD) still remains a challenge. Melatonin (MLT), acting through its two receptors MT1 and MT2, plays a key role in regulating circadian rhythms which are dysfunctional in BD. Using a translational approach, we examined the implication and potential of MT1 receptors...

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Bibliographic Details
Main Authors: Margherita Tassan Mazzocco, Claudia Pisanu, Luigi Russo, Clementina Acconcia, Marco Cambiaghi, Sofia De Girolamo, Alessio Squassina, Laura Cherchi, Elena Monzani, Francesca Scebba, Debora Angeloni, Danilo De Gregorio, Sofia Nasini, Stefano Dall’Acqua, Stefania Sut, Federico Suprani, Mario Garzilli, Beatrice Guiso, Vittoria Pulcinelli, Maria Novella Iaselli, Ilaria Pinna, Giulia Somaini, Laura Arru, Carolina Corrias, Pasquale Paribello, Federica Pinna, Gabriella Gobbi, Flavia Valtorta, Bernardo Carpiniello, Mirko Manchia, Stefano Comai
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Pharmacological Research
Subjects:
Bipolar disorder
Melatonin
MT1 receptor
UCM871
Clock gene
Nuclear Magnetic Resonance
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661823003493

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http://www.sciencedirect.com/science/article/pii/S1043661823003493

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