Effects of chronic caffeine intake and withdrawal on neural activity assessed via resting-state functional magnetic resonance imaging in mice

Effects of chronic caffeine intake and withdrawal on neural activity assessed via resting-state functional magnetic resonance imaging in mice

Caffeine is a psychoactive substance that not only improves wakefulness, but also slows the cognitive decline caused by aging. However, at present, there are no reports about the effects of caffeine withdrawal, including headaches and changes in brain functional networks (nerve activity). Headache m...

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Bibliographic Details
Main Authors: Mitsuki Rikitake, Sachiko Notake, Karen Kurokawa, Junichi Hata, Fumiko Seki, Yuji Komaki, Hinako Oshiro, Naoki Kawaguchi, Yawara Haga, Daisuke Yoshimaru, Ken Ito, Hirotaka James Okano
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Heliyon
Subjects:
Caffeine
Resting-state fMRI
Neural network
Independent component analysis
Functional connectivity analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402203002X

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http://www.sciencedirect.com/science/article/pii/S240584402203002X

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