Dapagliflozin attenuates residual cardiac remodeling after surgical ventricular reconstruction in mice with an enlarged heart after myocardial infarction

Dapagliflozin attenuates residual cardiac remodeling after surgical ventricular reconstruction in mice with an enlarged heart after myocardial infarction

Background: Severe heart failure refractory to conventional therapy requires alternative treatment modalities. Surgical ventricular reconstruction (SVR) has been used to reverse cardiac remodeling in post-myocardial infarction (MI) patients with large left ventricular (LV) aneurysm, however, residua...

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Bibliographic Details
Main Authors: Siyuan Ma, Lu Chen, Junyu Yan, Mengjia Shen, Rui Zhang, Mingjue Li, Mingyuan He, Kaitong Chen, Yingqi Zhu, Hairuo Lin, Yuegang Wang, Wangjun Liao, Jianping Bin, Cankun Zheng, Yulin Liao
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Surgical ventricular reconstruction
Dapagliflozin
Myocardial infarction
Residual cardiac remodeling
Cardiac metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222011544

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http://www.sciencedirect.com/science/article/pii/S0753332222011544

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