Pentoxifylline Inhibits Pulmonary Fibrosis by Regulating Cellular Senescence in Mice

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease, and its occurrence and development are mediated by cellular senescence. Drugs targeting senescent cells seem like a promising and efficacious strategy for IPF treatment. Previous studies have illustrated that pentoxifylline (PTX)...

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Bibliographic Details
Main Authors: Yifan Lin, Zhihao Xu, Beibei Zhou, Keer Ma, Mengyi Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.848263/full