Synthesis of aligned porous polyethylene glycol/silk fibroin/hydroxyapatite scaffolds for osteoinduction in bone tissue engineering

Synthesis of aligned porous polyethylene glycol/silk fibroin/hydroxyapatite scaffolds for osteoinduction in bone tissue engineering

Abstract Background The physical factors of the extracellular matrix have a profound influence on the differentiation behavior of mesenchymal stem cells. In this study, the effect of the biophysical microenvironment on rat bone marrow mesenchymal stem cell (BMSC) osteogenesis was studied both in vit...

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Main Authors: Yuchao Yang, Yanting Feng, Rongmei Qu, Qingtao Li, Dongming Rong, Tingyu Fan, Yiting Yang, Bing Sun, Zhenyu Bi, Asmat Ullah Khan, Ting Deng, Jingxing Dai, Jun Ouyang
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Stem Cell Research & Therapy
Subjects:
Hydroxyapatite
Stiffness
Extracellular matrix (ECM)
Bone marrow mesenchymal stem cells (BMSCs)
Osteogenesis
Osteoinduction
Online Access:https://doi.org/10.1186/s13287-020-02024-8

Internet

https://doi.org/10.1186/s13287-020-02024-8

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