13C-metabolic flux analysis of ethanol-assimilating Saccharomyces cerevisiae for S-adenosyl-l-methionine production

13C-metabolic flux analysis of ethanol-assimilating Saccharomyces cerevisiae for S-adenosyl-l-methionine production

Abstract Background Saccharomyces cerevisiae is a host for the industrial production of S-adenosyl-l-methionine (SAM), which has been widely used in pharmaceutical and nutritional supplement industries. It has been reported that the intracellular SAM content in S. cerevisiae can be improved by the a...

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Bibliographic Details
Main Authors: Kenshi Hayakawa, Fumio Matsuda, Hiroshi Shimizu
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Microbial Cell Factories
Subjects:
Saccharomyces cerevisiae
13C-based metabolic flux analysis
Ethanol metabolism
Central carbon metabolism
Redox balance
Online Access:http://link.springer.com/article/10.1186/s12934-018-0935-6

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http://link.springer.com/article/10.1186/s12934-018-0935-6

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