Whole-Genome Sequencing and Target Validation Analysis of Müllerian Adenosarcoma: A Tumor With Complex but Specific Genetic Alterations

Whole-Genome Sequencing and Target Validation Analysis of Müllerian Adenosarcoma: A Tumor With Complex but Specific Genetic Alterations

Mullerian adenosarcoma (MAS) is a biphasic tumor with malignant stroma. It is most commonly of endometrial origin but occasionally originates in the cervix, ovary, or other pelvic/peritoneal sites. The typical MAS is low grade with an indolent clinical course; however, tumors with sarcomatous overgr...

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Bibliographic Details
Main Authors: Yanli Ban, Jean V. Fischer, Kruti P. Maniar, Haiyang Guo, Chang Zeng, Yinuo Li, Qing Zhang, Xinkun Wang, Wei Zhang, Serdar E. Bulun, Jian-Jun Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Oncology
Subjects:
Müllerian adenosarcoma
whole-genome sequencing
copy number variation
pathway analysis
target gene mutations
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00538/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.00538/full

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