The Immunomodulatory Role of Microbiota in Rheumatic Heart Disease: What Do We Know and What Can We Learn from Other Rheumatic Diseases?

The Immunomodulatory Role of Microbiota in Rheumatic Heart Disease: What Do We Know and What Can We Learn from Other Rheumatic Diseases?

Rheumatic heart disease (RHD) represents a serious cardiac sequela of acute rheumatic fever, occurring in 30–45% of patients. RHD is multifactorial, with a strong familial predisposition and known environmental risk factors that drive loss of immunological tolerance. The gut and oral microbiome have...

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Bibliographic Details
Main Authors: Amira Kohil, Wafa Abdalla, Wisam N. Ibrahim, Khalid M. Al-Harbi, Amal Al-Haidose, Maha Al-Asmakh, Atiyeh M. Abdallah
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Medicina
Subjects:
rheumatic heart disease
microbiota
immunomodulation
autoimmunity
molecular mimicry
epitope spreading
Online Access:https://www.mdpi.com/1648-9144/59/9/1629

Internet

https://www.mdpi.com/1648-9144/59/9/1629

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