Dual‐Pronged Attack: pH‐Driven Membrane‐Anchored NIR Dual‐Type Nano‐Photosensitizer Excites Immunogenic Pyroptosis and Sequester Immune Checkpoint for Enhanced Prostate Cancer Photo‐Immunotherapy

Dual‐Pronged Attack: pH‐Driven Membrane‐Anchored NIR Dual‐Type Nano‐Photosensitizer Excites Immunogenic Pyroptosis and Sequester Immune Checkpoint for Enhanced Prostate Cancer Photo‐Immunotherapy

Abstract Prostate cancer (PCa) is a frustrating immunogenic “cold” tumor and generally receives unsatisfied immunotherapy outcomes in the clinic. Pyroptosis is an excellent immunogenic cell death form that can effectively activate the antitumor immune response, promote cytotoxic T‐lymphocyte infiltr...

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Bibliographic Details
Main Authors: He Wang, Zhangxin He, Yijian Gao, Dexiang Feng, Xuedong Wei, Yuhua Huang, Jianquan Hou, Shengliang Li, Weijie Zhang
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Advanced Science
Subjects:
immunotherapy
membrane anchoring
prostate cancer
pyroptosis
type I photosensitizer
Online Access:https://doi.org/10.1002/advs.202302422

Internet

https://doi.org/10.1002/advs.202302422

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