Structural Bases for the Regulation of CO Binding in the Archaeal Protoglobin from Methanosarcina acetivorans.

Structural Bases for the Regulation of CO Binding in the Archaeal Protoglobin from Methanosarcina acetivorans.

Studies of CO ligand binding revealed that two protein states with different ligand affinities exist in the protoglobin from Methanosarcina acetivorans (in MaPgb*, residue Cys(E20)101 was mutated to Ser). The switch between the two states occurs upon the ligation of MaPgb*. In this work, site-direct...

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Bibliographic Details
Main Authors: Lesley Tilleman, Stefania Abbruzzetti, Chiara Ciaccio, Giampiero De Sanctis, Marco Nardini, Alessandra Pesce, Filip Desmet, Luc Moens, Sabine Van Doorslaer, Stefano Bruno, Martino Bolognesi, Paolo Ascenzi, Massimo Coletta, Cristiano Viappiani, Sylvia Dewilde
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4457829?pdf=render

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http://europepmc.org/articles/PMC4457829?pdf=render

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