Population pharmacokinetics of intravenous Erwinia asparaginase in pediatric acute lymphoblastic leukemia patients

Population pharmacokinetics of intravenous Erwinia asparaginase in pediatric acute lymphoblastic leukemia patients

Erwinia asparaginase is an important component in the treatment of pediatric acute lymphoblastic leukemia. A large variability in serum concentrations has been observed after intravenous Erwinia asparaginase. Currently, Dutch Childhood Oncology Group protocols dose alterations are based on trough co...

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Bibliographic Details
Main Authors: Sebastiaan D.T. Sassen, Ron A.A. Mathôt, Rob Pieters, Robin Q.H. Kloos, Valérie de Haas, Gertjan J.L. Kaspers, Cor van den Bos, Wim J.E. Tissing, Maroeska te Loo, Marc B. Bierings, Wouter J.W. Kollen, Christian M. Zwaan, Inge M. van der Sluis
Format: Article
Language:English
Published: Ferrata Storti Foundation 2017-03-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/8006

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https://haematologica.org/article/view/8006

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