Transcriptional Circuit Fragility Influences HIV Proviral Fate

Summary: Transcriptional circuit architectures in several organisms have been evolutionarily selected to dictate precise given responses. Unlike these cellular systems, HIV is regulated through a complex circuit composed of two successive phases (host and viral), which create a positive feedback loo...

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Bibliographic Details
Main Authors: Emily L. Morton, Christian V. Forst, Yue Zheng, Ana B. DePaula-Silva, Nora-Guadalupe P. Ramirez, Vicente Planelles, Iván D’Orso
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719303146