Magnetic-Driven Hydrogel Microrobots Selectively Enhance Synthetic Lethality in MTAP-Deleted Osteosarcoma

Magnetic-Driven Hydrogel Microrobots Selectively Enhance Synthetic Lethality in MTAP-Deleted Osteosarcoma

Background: Drugs based on synthetic lethality have advantages such as inhibiting tumor growth and affecting normal tissue in vivo. However, specific targets for osteosarcoma have not been acknowledged yet. In this study, a non-targeted but controllable drug delivery system has been applied to selec...

Full description

Bibliographic Details
Main Authors: Haoran Mu, Chenlu Liu, Qi Zhang, Huanliang Meng, Shimin Yu, Ke Zeng, Jing Han, Xinmeng Jin, Shi Shi, Peiyao Yu, Tianlong Li, Jing Xu, Yingqi Hua
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
microrobots
osteosarcoma
drug delivery system
MTAP deletion
PRMT5
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.911455/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.911455/full

Similar Items