Mural Serum Response Factor (SRF) Deficiency Provides Insights into Retinal Vascular Functionality and Development

Mural Serum Response Factor (SRF) Deficiency Provides Insights into Retinal Vascular Functionality and Development

Serum response factor (SRF) controls the expression of muscle contraction and motility genes in mural cells (MCs) of the vasculature. In the retina, MC-SRF is important for correct angiogenesis during development and the continuing maintenance of the vascular tone. The purpose of this study was to p...

Full description

Bibliographic Details
Main Authors: Alexander Günter, Vithiyanjali Sothilingam, Michael M. Orlich, Alfred Nordheim, Mathias W. Seeliger, Regine Mühlfriedel
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
serum response factor
mural cells
retinal ischemia
murine disease models
vascular smooth-muscle cells
retinal imaging
Online Access:https://www.mdpi.com/1422-0067/24/16/12597

Internet

https://www.mdpi.com/1422-0067/24/16/12597

Similar Items