3D reconstruction of skin and spatial mapping of immune cell density, vascular distance and effects of sun exposure and aging

Abstract Mapping the human body at single cell resolution in three dimensions (3D) is important for understanding cellular interactions in context of tissue and organ organization. 2D spatial cell analysis in a single tissue section may be limited by cell numbers and histology. Here we show a workfl...

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Bibliographic Details
Main Authors: Soumya Ghose, Yingnan Ju, Elizabeth McDonough, Jonhan Ho, Arivarasan Karunamurthy, Chrystal Chadwick, Sanghee Cho, Rachel Rose, Alex Corwin, Christine Surrette, Jessica Martinez, Eric Williams, Anup Sood, Yousef Al-Kofahi, Louis D. Falo, Katy Börner, Fiona Ginty
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04991-z