The Role of NLRP3 Inflammasome in Pneumococcal Infections

Inflammasomes are innate immune sensors that regulate caspase-1 mediated inflammation in response to environmental, host- and pathogen-derived factors. The NLRP3 inflammasome is highly versatile as it is activated by a diverse range of stimuli. However, excessive or chronic inflammasome activation a...

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Bibliographic Details
Main Authors: Surabhi Surabhi, Fabian Cuypers, Sven Hammerschmidt, Nikolai Siemens
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.614801/full