The Role of NLRP3 Inflammasome in Pneumococcal Infections

The Role of NLRP3 Inflammasome in Pneumococcal Infections

Inflammasomes are innate immune sensors that regulate caspase-1 mediated inflammation in response to environmental, host- and pathogen-derived factors. The NLRP3 inflammasome is highly versatile as it is activated by a diverse range of stimuli. However, excessive or chronic inflammasome activation a...

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Bibliographic Details
Main Authors:	Surabhi Surabhi, Fabian Cuypers, Sven Hammerschmidt, Nikolai Siemens
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-12-01
Series:	Frontiers in Immunology
Subjects:	nucleotide-binding and oligomerization domain-like receptors and pyrin domain containing receptor 3 inflammasome pneumococcus (Streptococcus pneumoniae) respiratory infection immune response
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2020.614801/full

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