IK1 channels do not contribute to the slow afterhyperpolarization in pyramidal neurons

IK1 channels do not contribute to the slow afterhyperpolarization in pyramidal neurons

In pyramidal neurons such as hippocampal area CA1 and basolateral amygdala, a slow afterhyperpolarization (sAHP) follows a burst of action potentials, which is a powerful regulator of neuronal excitability. The sAHP amplitude increases with aging and may underlie age related memory decline. The sAHP...

Full description

Bibliographic Details
Main Authors: Kang Wang, Pedro Mateos-Aparicio, Christoph Hönigsperger, Vijeta Raghuram, Wendy W Wu, Margreet C Ridder, Pankaj Sah, Jim Maylie, Johan F Storm, John P Adelman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-01-01
Series:eLife
Subjects:
HEK293
Afterhyperpolarization
sAHP
IK1
TRAM-34
KCNN4
Online Access:https://elifesciences.org/articles/11206

Internet

https://elifesciences.org/articles/11206

Similar Items