Activation of NLRP3 inflammasome in lung epithelial cells triggers radiation-induced lung injury

Activation of NLRP3 inflammasome in lung epithelial cells triggers radiation-induced lung injury

Abstract Background Radiation-induced lung injury (RILI) is the most common and serious complication of chest radiotherapy. However, reported radioprotective agents usually lead to radiation resistance in tumor cells. The key to solving this problem is to distinguish between the response of tumor ce...

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Bibliographic Details
Main Authors: Xinrui Rao, Dong Zhou, Huilin Deng, Yunshang Chen, Jian Wang, Xiaoshu Zhou, Xiaohua Jie, Yingzhuo Xu, Zilong Wu, Geng Wang, Xiaorong Dong, Sheng Zhang, Rui Meng, Chuangyan Wu, Shijie Xing, Kai Fan, Gang Wu, Rui Zhou
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Respiratory Research
Subjects:
Radiation-induced lung injury
Lung fibrosis
Inflammasomes
NLRP3
Glucose metabolism
Online Access:https://doi.org/10.1186/s12931-023-02331-7

Internet

https://doi.org/10.1186/s12931-023-02331-7

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