Simplification of culture conditions and feeder-free expansion of bovine embryonic stem cells

Abstract Bovine embryonic stem cells (bESCs) extend the lifespan of the transient pluripotent bovine inner cell mass in vitro. After years of research, derivation of stable bESCs was only recently reported. Although successful, bESC culture relies on complex culture conditions that require a custom-...

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Bibliographic Details
Main Authors: Delia Alba Soto, Micaela Navarro, Canbin Zheng, Michelle Margaret Halstead, Chuan Zhou, Carly Guiltinan, Jun Wu, Pablo Juan Ross
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90422-0