CD40 Pathway and IL-2 Expression Mediate the Differential Outcome of Colorectal Cancer Patients with Different <i>CSF1R</i> c.1085 Genotypes

CD40 Pathway and IL-2 Expression Mediate the Differential Outcome of Colorectal Cancer Patients with Different <i>CSF1R</i> c.1085 Genotypes

Colony-stimulating factor 1 receptor (CSF-1R) acts as the receptor for colony stimulating factor 1, a cytokine that controls the production, differentiation, and function of macrophages. Prior studies showed cancer patients harboring germline <i>CSF1R</i> c.1085A>G genetic variant had...

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Bibliographic Details
Main Authors: Yu-Min Yeh, Peng-Chan Lin, Wu-Chou Su, Meng-Ru Shen
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
colony-stimulating factor 1 receptor
genetic variant
CD40
IL-2 expression
colorectal cancer
Online Access:https://www.mdpi.com/1422-0067/22/22/12565

Internet

https://www.mdpi.com/1422-0067/22/22/12565

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