Investigating the physiology of viable but non-culturable bacteria by microfluidics and time-lapse microscopy

Investigating the physiology of viable but non-culturable bacteria by microfluidics and time-lapse microscopy

Abstract Background Clonal microbial populations often harbor rare phenotypic variants that are typically hidden within the majority of the remaining cells, but are crucial for the population’s resilience to external perturbations. Persister and viable but non-culturable (VBNC) cells are two importa...

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Bibliographic Details
Main Authors: Rosemary A. Bamford, Ashley Smith, Jeremy Metz, Georgina Glover, Richard W. Titball, Stefano Pagliara
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Biology
Subjects:
Viable but non-culturable cells
Microfluidics
Escherichia coli
Persisters
Single-cell
Antibiotic tolerance
Online Access:http://link.springer.com/article/10.1186/s12915-017-0465-4

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http://link.springer.com/article/10.1186/s12915-017-0465-4

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