Association between colorectal cancer, the frequency of Bacteroides fragilis, and the level of mismatch repair genes expression in the biopsy samples of Iranian patients

Association between colorectal cancer, the frequency of Bacteroides fragilis, and the level of mismatch repair genes expression in the biopsy samples of Iranian patients

Abstract Background Deficient DNA mismatch repair (MMR) can cause microsatellite instability (MSI) and is more common in colorectal cancer (CRC) patients. Understanding the carcinogenic mechanism of bacteria and their impact on cancer cells is crucial. Bacteroides fragilis (B. fragilis) has been ide...

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Bibliographic Details
Main Authors: Nooshin Nazarinejad, Bahareh Hajikhani, Amir Abbas Vaezi, Farzaneh Firoozeh, Fatemeh Sameni, Somayeh Yaslianifard, Mehdi Goudarzi, Masoud Dadashi
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Gastroenterology
Subjects:
Colorectal cancer
mlh1
msh2
msh6
Bacteroides fragilis
Online Access:https://doi.org/10.1186/s12876-024-03169-z

Internet

https://doi.org/10.1186/s12876-024-03169-z

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