RNA editing regulates glutamatergic synapses in the frontal cortex of a molecular subtype of Amyotrophic Lateral Sclerosis

RNA editing regulates glutamatergic synapses in the frontal cortex of a molecular subtype of Amyotrophic Lateral Sclerosis

Abstract Background Amyotrophic Lateral Sclerosis (ALS) is a highly heterogenous neurodegenerative disorder that primarily affects upper and lower motor neurons, affecting additional cell types and brain regions. Underlying molecular mechanisms are still elusive, in part due to disease heterogeneity...

Full description

Bibliographic Details
Main Authors: Korina Karagianni, Dimitra Dafou, Konstantinos Xanthopoulos, Theodoros Sklaviadis, Eirini Kanata
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Molecular Medicine
Subjects:
Amyotrophic Lateral Sclerosis
Molecular subtype
ALS-Ox
RNA editing
Frontal cortex
Glutamatergic synapse
Online Access:https://doi.org/10.1186/s10020-024-00863-2

Internet

https://doi.org/10.1186/s10020-024-00863-2

Similar Items