PGM1 suppresses colorectal cancer cell migration and invasion by regulating the PI3K/AKT pathway

Abstract Background Phosphoglucomutase 1 (PGM1) is known for its involvement in cancer pathogenesis. However, its biological role in colorectal cancer (CRC) has remained unknown. Here, we studied the functions and mechanisms of PGM1 in CRC. Methods We verified PGM-1 as a differentially expressed gen...

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Bibliographic Details
Main Authors: Zhewen Zheng, Xue Zhang, Jian Bai, Long Long, Di Liu, Yunfeng Zhou
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-022-02545-7