Needle-free, spirulina-produced Plasmodium falciparum circumsporozoite vaccination provides sterile protection against pre-erythrocytic malaria in mice

Needle-free, spirulina-produced Plasmodium falciparum circumsporozoite vaccination provides sterile protection against pre-erythrocytic malaria in mice

Abstract Antibodies against the Plasmodium falciparum circumsporozoite protein (PfCSP) can block hepatocyte infection by sporozoites and protect against malaria. Needle-free vaccination strategies are desirable, yet most PfCSP-targeted vaccines like RTS,S require needle-based administration. Here, w...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Tracy Saveria, Chaitra Parthiban, Annette M. Seilie, Colin Brady, Anissa Martinez, Ridhima Manocha, Esha Afreen, Hui Zhao, Ashley Krzeszowski, Jeremy Ferrara, Troy Paddock, James Roberts, Brad C. Stone, Michael Tasch, Sean C. Murphy
स्वरूप: लेख
भाषा:English
प्रकाशित: Nature Portfolio 2022-10-01
श्रृंखला:npj Vaccines
ऑनलाइन पहुंच:https://doi.org/10.1038/s41541-022-00534-5

इंटरनेट

https://doi.org/10.1038/s41541-022-00534-5

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