Microglial depletion disrupts normal functional development of adult-born neurons in the olfactory bulb
Microglia play key roles in regulating synapse development and refinement in the developing brain, but it is unknown whether they are similarly involved during adult neurogenesis. By transiently depleting microglia from the healthy adult mouse brain, we show that microglia are necessary for the norm...
Main Authors: | Jenelle Wallace, Julia Lord, Lasse Dissing-Olesen, Beth Stevens, Venkatesh N Murthy |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/50531 |
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