Reporting methodological issues of the mendelian randomization studies in health and medical research: a systematic review

Reporting methodological issues of the mendelian randomization studies in health and medical research: a systematic review

Abstract Background Mendelian randomization (MR) studies using Genetic risk scores (GRS) as an instrumental variable (IV) have increasingly been used to control for unmeasured confounding in observational healthcare databases. However, proper reporting of methodological issues is sparse in these stu...

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Bibliographic Details
Main Authors: Shabab Noor Islam, Tanvir Ahammed, Aniqua Anjum, Olayan Albalawi, Md. Jamal Uddin
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Medical Research Methodology
Subjects:
Instrumental variable analysis (IV)
Mendelian randomization
Genetic risk scores
Systematic review
Online Access:https://doi.org/10.1186/s12874-022-01504-0

Internet

https://doi.org/10.1186/s12874-022-01504-0

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