A planar polarized MYO6-DOCK7-RAC1 axis promotes tissue fluidification in mammary epithelia

Summary: Tissue fluidification and collective motility are pivotal in regulating embryonic morphogenesis, wound healing, and tumor metastasis. These processes frequently require that each cell constituent of a tissue coordinates its migration activity and directed motion through the oriented extensi...

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Main Authors: Luca Menin, Janine Weber, Stefano Villa, Emanuele Martini, Elena Maspero, Carlos A. Niño, Valeria Cancila, Alessandro Poli, Paolo Maiuri, Andrea Palamidessi, Emanuela Frittoli, Fabrizio Bianchi, Claudio Tripodo, Kylie J. Walters, Fabio Giavazzi, Giorgio Scita, Simona Polo
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723010124