Gut microbiota in a mouse model of obesity and peripheral neuropathy associated with plasma and nerve lipidomics and nerve transcriptomics

Gut microbiota in a mouse model of obesity and peripheral neuropathy associated with plasma and nerve lipidomics and nerve transcriptomics

Abstract Background Peripheral neuropathy (PN) is a common complication in obesity, prediabetes, and type 2 diabetes, though its pathogenesis remains incompletely understood. In a murine high-fat diet (HFD) obesity model of PN, dietary reversal (HFD-R) to a low-fat standard diet (SD) restores nerve...

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Bibliographic Details
Main Authors: Kai Guo, Claudia Figueroa-Romero, Mohamed Noureldein, Lucy M. Hinder, Stacey A. Sakowski, Amy E. Rumora, Hayley Petit, Masha G. Savelieff, Junguk Hur, Eva L. Feldman
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Microbiome
Subjects:
Peripheral neuropathy
Dysbiosis
Lipids
Microbiome
Obesity
Omics
Online Access:https://doi.org/10.1186/s40168-022-01436-3

Internet

https://doi.org/10.1186/s40168-022-01436-3

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