Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity

Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity

Abstract Background People with diabetes are more likely to develop tuberculosis (TB) and to have poor TB‐treatment outcomes than those without. We previously showed that blood transcriptomes in people with TB‐diabetes (TB‐DM) co‐morbidity have excessive inflammatory and reduced interferon responses...

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Main Authors: Clare Eckold, Cassandra L. R. vanDoorn, Rovina Ruslami, Katharina Ronacher, Anca‐Lelia Riza, Suzanne vanVeen, Ji‐Sook Lee, Vinod Kumar, Sarah Kerry‐Barnard, Stephanus T. Malherbe, Léanie Kleynhans, Kim Stanley, Simone A. Joosten, Julia A Critchley, Philip C. Hill, Reinout vanCrevel, Cisca Wijmenga, Mariëlle C. Haks, Mihai Ioana, Bachti Alisjahbana, Gerhard Walzl, Tom H. M. Ottenhoff, Hazel M. Dockrell, Eleonora Vianello, Jacqueline M. Cliff, the TANDEM Consortium$
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Clinical and Translational Medicine
Subjects:
diabetes
transcriptome
treatment
tuberculosis
Online Access:https://doi.org/10.1002/ctm2.1375

Internet

https://doi.org/10.1002/ctm2.1375

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