In vitro characterization of 3D culture-based differentiation of human liver stem cells

In vitro characterization of 3D culture-based differentiation of human liver stem cells

Introduction: The lack of functional hepatocytes poses a significant challenge for drug safety testing and therapeutic applications due to the inability of mature hepatocytes to expand and their tendency to lose functionality in vitro. Previous studies have demonstrated the potential of Human Liver...

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Bibliographic Details
Main Authors: Marta Tapparo, Gabriele Saccu, Chiara Pasquino, Valentina Fonsato, Claudio Medana, Valentina Schiavo, Enrica Mecarelli, Monica Maccagno, Lorenzo Silengo, Stefania Bruno, Giovanni Camussi, Maria Beatriz Herrera Sanchez
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
differentiation
human liver stem cells
rotary cell culture system
Indocyanine green
urea cycle
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1352013/full

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https://www.frontiersin.org/articles/10.3389/fcell.2024.1352013/full

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