Enhanced IL-17 Producing and Maintained Cytolytic Effector Functions of Gut Mucosal CD161<sup>+</sup>CD8<sup>+</sup> T Cells in SIV-Infected Rhesus Macaques

Enhanced IL-17 Producing and Maintained Cytolytic Effector Functions of Gut Mucosal CD161<sup>+</sup>CD8<sup>+</sup> T Cells in SIV-Infected Rhesus Macaques

Previous studies have indicated that the loss of CD161-expressing CD4<sup>+</sup> Th17 cells is linked to the progression of chronic HIV. These cells are significantly depleted in peripheral blood and gut mucosa of HIV-infected individuals, contributing to inflammation and disruption of...

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Bibliographic Details
Main Authors:	Siva Thirugnanam, Edith M. Walker, Faith Schiro, Pyone P. Aye, Jay Rappaport, Namita Rout
Format:	Article
Language:	English
Published:	MDPI AG 2023-09-01
Series:	Viruses
Subjects:	mucosal immunity T cells CD161 SIV IL-17 TNF-α
Online Access:	https://www.mdpi.com/1999-4915/15/9/1944

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