Upregulation of LRRK2 following traumatic brain injury does not directly phosphorylate Thr175 tau

Phosphorylated microtubule-associated protein tau (tau) aggregates are a pathological hallmark of various neurodegenerative diseases, including chronic traumatic encephalopathy and amyotrophic lateral sclerosis with cognitive impairment. While there are many residues phosphorylated on tau, phosphory...

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Bibliographic Details
Main Authors: Neil Donison, Matthew Hintermayer, Maegha Subramaniam, Erin Santandrea, Kathryn Volkening, Michael J. Strong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1272899/full