Angioedema Caused by Drugs That Prevent the Degradation of Vasoactive Peptides: A Pharmacovigilance Database Study

Angioedema Caused by Drugs That Prevent the Degradation of Vasoactive Peptides: A Pharmacovigilance Database Study

Angioedema results from the decreased degradation of vasoactive peptides such as substance P and bradykinin. In this study, we sought to clarify whether dipeptidyl peptidase-4 (DPP-4) and angiotensin-converting enzyme (ACE) inhibitors that suppress the degradation of substance P and bradykinin are i...

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Bibliographic Details
Main Authors: Yoshihiro Noguchi, Azusa Murayama, Hiroki Esaki, Mayuko Sugioka, Aisa Koyama, Tomoya Tachi, Hitomi Teramachi
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Journal of Clinical Medicine
Subjects:
angiotensin-converting enzyme (ACE) inhibitors
dipeptidyl peptidase-4 (DPP-4) inhibitors
angioedema
Bayesian Confidence Propagation Neural Network (BCPNN)
Japanese Adverse Drug Event Report (JADER) database
Online Access:https://www.mdpi.com/2077-0383/10/23/5507

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https://www.mdpi.com/2077-0383/10/23/5507

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