DC vaccines loaded with glioma cells killed by photodynamic therapy induce Th17 anti-tumor immunity and provide a four-gene signature for glioma prognosis

Abstract Gliomas, the most frequent type of primary tumor of the central nervous system in adults, results in significant morbidity and mortality. Despite the development of novel, complex, multidisciplinary, and targeted therapies, glioma therapy has not progressed much over the last decades. There...

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Bibliographic Details
Main Authors: Maria Vedunova, Victoria Turubanova, Olga Vershinina, Maria Savyuk, Iuliia Efimova, Tatiana Mishchenko, Robrecht Raedt, Anne Vral, Christian Vanhove, Daria Korsakova, Claus Bachert, Frauke Coppieters, Patrizia Agostinis, Abhishek D. Garg, Mikhail Ivanchenko, Olga Krysko, Dmitri V. Krysko
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05514-0