Aggregation is a critical cause of poor transfer into the brain tissue of intravenously administered cationic PAMAM dendrimer nanoparticles

Yoshika Kurokawa,1 Hideko Sone,1 Tin-Tin Win-Shwe,1 Yang Zeng,1 Hiroyuki Kimura,2 Yosuke Koyama,1 Yusuke Yagi,2 Yasuto Matsui,3 Masashi Yamazaki,4 Seishiro Hirano1 1Center for Health and Environmental Risk Research, National Institute for Environmental Studies, Tsukuba, Ibaraki, 2Department of Anal...

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Bibliographic Details
Main Authors: Kurokawa Y, Sone H, Win-Shwe TT, Zeng Y, Kimura H, Koyama Y, Yagi Y, Matsui Y, Yamazaki M, Hirano S
Format: Article
Language:English
Published: Dove Medical Press 2017-05-01
Series:International Journal of Nanomedicine
Subjects:
Online Access:https://www.dovepress.com/aggregation-is-a-critical-cause-of-poor-transfer-into-the-brain-tissue-peer-reviewed-article-IJN