Antepartum Aspirin Administration Reduces Activin A and Cardiac Global Longitudinal Strain in Preeclamptic Women

Antepartum Aspirin Administration Reduces Activin A and Cardiac Global Longitudinal Strain in Preeclamptic Women

Background Approximately 60% of women have Stage B heart failure 1 year after a preeclamptic delivery. Emerging evidence suggests that the profibrotic growth factor activin A, which has been shown to induce cardiac fibrosis and hypertrophy, is elevated in preeclampsia and may be inhibited by aspirin...

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Bibliographic Details
Main Authors: Heba Naseem, John Dreixler, Ariel Mueller, Avery Tung, Rohin Dhir, Rachna Chibber, Abid Fazal, Joey P. Granger, Bhavisha A. Bakrania, Victoria deMartelly, Sarosh Rana, Sajid Shahul
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
activin A
aspirin
cardiac dysfunction
global longitudinal strain
pregnancy
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.015997

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https://www.ahajournals.org/doi/10.1161/JAHA.119.015997

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