Retrospective study of transcriptomic profiling identifies Thai triple-negative breast cancer patients who may benefit from immune checkpoint and PARP inhibitors

Retrospective study of transcriptomic profiling identifies Thai triple-negative breast cancer patients who may benefit from immune checkpoint and PARP inhibitors

Background Triple-negative breast cancer (TNBC) is a rare and aggressive breast cancer subtype. Unlike the estrogen receptor-positive subtype, whose recurrence risk can be predicted by gene expression-based signature, TNBC is more heterogeneous, with diverse drug sensitivity levels to standard regim...

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Bibliographic Details
Main Authors: Monthira Suntiparpluacha, Jantappapa Chanthercrob, Doonyapat Sa-nguanraksa, Juthamas Sitthikornpaiboon, Amphun Chaiboonchoe, Patipark Kueanjinda, Natini Jinawath, Somponnat Sampattavanich
Format: Article
Language:English
Published: PeerJ Inc. 2023-06-01
Series:PeerJ
Subjects:
Gene expression
Triple-negative breast cancer
Subtype
NanoString nCounter
Online Access:https://peerj.com/articles/15350.pdf

Internet

https://peerj.com/articles/15350.pdf

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