Oscillatory shear stress promotes vein graft intimal hyperplasia via NADPH oxidase-related pathways

Oscillatory shear stress promotes vein graft intimal hyperplasia via NADPH oxidase-related pathways

BackgroundUncontrolled intimal hyperplasia (IH) after autologous saphenous vein grafting triggers a high restenosis rate; however, its association with the activation of NADPH oxidase (NOX)-related pathways is unclear. Here, we investigated the effects and mechanism of oscillatory shear stress (OSS)...

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Bibliographic Details
Main Authors: Guoqing Yao, Huanhuan Li, Xiangyi Zuo, Chunkai Wang, Yelei Xiao, Yu Zhao, Xuehu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Surgery
Subjects:
oscillating shear stress
endothelial proliferation
NOX
reactive oxygen species
revascularization
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2023.1073557/full

Internet

https://www.frontiersin.org/articles/10.3389/fsurg.2023.1073557/full

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