Oscillatory shear stress promotes vein graft intimal hyperplasia via NADPH oxidase-related pathways
BackgroundUncontrolled intimal hyperplasia (IH) after autologous saphenous vein grafting triggers a high restenosis rate; however, its association with the activation of NADPH oxidase (NOX)-related pathways is unclear. Here, we investigated the effects and mechanism of oscillatory shear stress (OSS)...
Main Authors: | Guoqing Yao, Huanhuan Li, Xiangyi Zuo, Chunkai Wang, Yelei Xiao, Yu Zhao, Xuehu Wang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-02-01
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Series: | Frontiers in Surgery |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1073557/full |
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