Identification of a novel aminoglycoside O-nucleotidyltransferase AadA33 in Providencia vermicola

Identification of a novel aminoglycoside O-nucleotidyltransferase AadA33 in Providencia vermicola

A novel chromosome-encoded aminoglycoside O-nucleotidyltransferase AadA33 was identified in Providencia vermicola strain P13. The AadA33 shares the highest amino acid identity of 51.28% with the function characterized AadA31. Antibiotic susceptibility testing and enzyme kinetics analysis revealed th...

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Bibliographic Details
Main Authors: Chunlin Feng, Mengdi Gao, Weiyan Jiang, Weina Shi, Anqi Li, Shuang Liu, Lei Zhang, Xueya Zhang, Qiaoling Li, Hailong Lin, Junwan Lu, Kewei Li, Hailin Zhang, Yunliang Hu, Qiyu Bao, Xi Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Microbiology
Subjects:
aminoglycoside O-nucleotidyltransferase
AadA33
Providencia vermicola
enzyme kinetics
novel antimicrobial resistance gene
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.990739/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2022.990739/full

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