Tumor-derived exosomal linc00881 induces lung fibroblast activation and promotes osteosarcoma lung migration

Tumor-derived exosomal linc00881 induces lung fibroblast activation and promotes osteosarcoma lung migration

Abstract Osteosarcoma (OS) commonly metastasizes to the lung, yet the underlying molecular mechanisms remain poorly understood. Exosomes play a crucial role in tumor migration, including OS lung migration. However, the underlying mechanism by which exosome-derived long non-coding RNAs (lncRNAs) cont...

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Bibliographic Details
Main Authors: Xinyu Chang, Qiuyu Tan, Jinwen Xu, Xu Wu, Ying Wang, Yuan Zhang, Hao Zhang, Haijun Liu, Liang Yan
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Cancer Cell International
Subjects:
linc00881
MMP2
Lung fibroblast activation
Lung migration
Osteosarcoma
Online Access:https://doi.org/10.1186/s12935-023-03121-3

Internet

https://doi.org/10.1186/s12935-023-03121-3

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