Plasma norepinephrine in hypertensive rats reflects α2-adrenoceptor release control only when re-uptake is inhibited

Plasma norepinephrine in hypertensive rats reflects α2-adrenoceptor release control only when re-uptake is inhibited

α2 adrenoceptors (AR) lower central sympathetic output and peripheral catecholamine release, thereby protecting against sympathetic hyperactivity and hypertension. Norepinephrine re-uptake transporter effectively (NET) removes norepinephrine from the synapse. Overflow to plasma will therefore not re...

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Bibliographic Details
Main Authors: Torill eBerg, Sven Ivar eWalaas, Bjørg Åse eRoberg, Trang Thi eHuynh, Jørgen eJensen
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Neurology
Subjects:
Epinephrine
Hypertension
α2 adrenoceptors
norepinephrine re-uptake transporter
catecholamine release
sympathetic nervous system activity
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2012.00160/full

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http://journal.frontiersin.org/Journal/10.3389/fneur.2012.00160/full

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