XBP1 modulates endoplasmic reticulum and mitochondria crosstalk via regulating NLRP3 in renal ischemia/reperfusion injury

XBP1 modulates endoplasmic reticulum and mitochondria crosstalk via regulating NLRP3 in renal ischemia/reperfusion injury

Abstract The functional status of mitochondria and the endoplasmic reticulum are central to renal ischemia/reperfusion injury (IRI). X-box binding protein 1 (XBP1) is an important transcription factor in endoplasmic reticulum stress. NLR family pyrin domain containing-3 (NLRP3) inflammatory bodies a...

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Bibliographic Details
Main Authors: Haiqiang Ni, Zhiyu Ou, Yuchen Wang, Yanna Liu, Kailun Sun, Ji Zhang, Jiasi Zhang, Wenfeng Deng, Wenli Zeng, Renfei Xia, Jian Xu, Nianqiao Gong, Yun Miao
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01360-x

Internet

https://doi.org/10.1038/s41420-023-01360-x

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